Table 5.
Comparison between the three studied groups according to Feret’s diameter of the renal corpuscle, perimeter of the renal corpuscle, percentage of the surface area of Bowman’s space, circularity of the renal corpuscle, and basement membrane thickness in micrometer
Control (n = 10) | Cisplatin treated (n = 10) | PRP treated (n = 10) | F | p | |
---|---|---|---|---|---|
Feret’s diameter of the renal corpuscle | |||||
Min.–Max. | 105.58–130.23 | 130.71–191.26 | 110.66–150.13 | 20.712* | <0.001* |
Mean ± SD. | 117.49 ± 9.04 | 161.96 ± 23.79 | 126.15 ± 12.55 | ||
Median | 120.21 | 167.82 | 125.79 | ||
p1 | <0.001* | 0.473 | |||
p2 | <0.001* | ||||
Perimeter of the renal corpuscle | |||||
Min.–Max. | 296.9–308.4 | 313.3–397.3 | 298.2–304.8 | 42.493* | <0.001* |
Mean ± SD. | 302.1 ± 3.46 | 356.9 ± 26.18 | 302.4 ± 2.27 | ||
Median | 302.4 | 360.1 | 303.2 | ||
p1 | <0.001* | 0.999 | |||
p2 | <0.001* | ||||
Percentage of the surface area of Bowman’s space | |||||
Min.–Max. | 13.09–21.38 | 28.11–77.19 | 13.09–21.38 | 42.248* | <0.001* |
Mean ± SD. | 15.89 ± 2.55 | 45.94 ± 14.35 | 15.31 ± 2.38 | ||
Median | 14.64 | 43.73 | 14.59 | ||
p1 | <0.001* | 0.987 | |||
p2 | <0.001* | ||||
Circularity of the renal corpuscle | |||||
Min.–max. | 0.967–0.990 | 0.877–0.910 | 0.959–0.975 | 308.106* | <0.001* |
Mean ± SD. | 0.973 ± 0.007 | 0.896 ± 0.010 | 0.967 ± 0.006 | ||
Median | 0.971 | 0.900 | 0.969 | ||
p1 | <0.001* | 0.275 | |||
p2 | <0.001* | ||||
Basement membrane thickness in micrometer | |||||
Min.–Max. | 0.77–0.97 | 1.87–2.15 | 0.97–1.97 | 33.952* | <0.001* |
Mean ± SD. | 0.87 ± 0.09 | 2.03 ± 0.11 | 1.47 ± 0.36 | ||
Median | 0.87 | 2.05 | 1.44 | ||
p1 | <0.001* | 0.003* | |||
p2 | 0.005* |
SD, standard deviation
F, F for one-way ANOVA test, pairwise comparison bet. each 2 groups was done using post hoc test (Tukey)
p, p value for comparing between the three studied groups
p1, p value for comparing between control and each other groups
p2, p value for comparing between cisplatin treated and PRP treated
*Statistically significant at p ≤ 0.05