Supplementary Table 2.

Quality assessment (animal study)

	Selection bias			Performance bias		Detection bias		Attrition bias h	Reporting bias i	Other j	Total score
	a	b	c	d	e	f	g
Sánchez-Tapia et al., 2019	yes	yes	unclear	yes	no	unclear	no	yes	yes	yes	6
Elayaraja et al., 2020	yes	yes	unclear	yes	no	yes	no	yes	yes	yes	7
Singh et al., 2010	yes	yes	unclear	yes	no	unclear	no	yes	yes	yes	6

*a, Sequence generation; b, Baseline characteristics; c, Allocation concealment; d, Random housing; e, Blinding; f, Random outcome assessment; g, Blinding; h, Incomplete outcome data; I, Selective outcome reporting; j, Other sources of bias