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. 2023 Nov 27;11(1):390–399. doi: 10.1002/ehf2.14594

Table 3.

Classification according to the HLM, NYHA, ACC/AHA, and LVEF at 12 months of follow‐up

Classification type Total population (N = 1720; 100%) No composite event (N = 1200; 100%) Composite event (N = 520; 100%) P‐value
H (1) 173 (10.1) 141 (11.7) 33 (6.3) <0.001
(2) 852 (49.5) 643 (53.6) 209 (40.2)
(3) 444 (25.8) 282 (23.5) 162 (31.2)
(4) 251 (14.6) 135 (11.2) 116 (22.3)
L (0) 505 (29.4) 417 (34.8) 88 (16.9) <0.001
(1) 371 (21.6) 267 (22.2) 104 (20)
(2) 573 (33.3) 383 (31.9) 190 (36.5)
(3) 271 (15.8) 133 (11.1) 138 (26.5)
M (0) 446 (25.9) 354 (29.5) 92 (17.7) <0.001
(1) 577 (33.5) 411 (34.2) 166 (31.9)
(2) 481 (28) 321 (26.8) 160 (30.8)
(3) 216 (12.6) 114 (9.5) 102 (19.6)
HLM (1) 373 (21.7) 311 (25.9) 62 (11.9) <0.001
(2) 507 (29.5) 392 (32.7) 115 (22.1)
(3) 587 (34.1) 371 (30.9) 216 (41.5)
(4) 253 (14.7) 126 (10.5) 127 (24.4)
NYHA (I) 321 (18.7) 249 (20.8) 72 (13.8) <0.001
(II) 488 (28.4) 361 (30.1) 127 (24.4)
(III) 626 (36.4) 424 (35.3) 202 (38.8)
(IV) 285 (16.6) 166 (13.8) 119 (22.9)
ACC/AHA (A) 144 (8.4) 117 (9.8) 27 (5.2) <0.001
(B) 687 (39.9) 507 (42.2) 180 (34.6)
(C) 449 (26.1) 323 (26.9) 126 (24.2)
(D) 440 (25.6) 253 (21.1) 187 (36)
LVEF pEF 812 (47.2) 616 (51.3) 196 (37.7) <0.001
mrEF 297 (17.3) 201 (16.8) 96 (18.5)
rEF 611 (35.5) 383 (31.9) 228 (43.8)

ACC/AHA, American College of Cardiology/American Heart Association; HLM, heart, lungs, and systemic multiorgan involvement; LVEF, left ventricular ejection fraction; mrEF, mildly reduced ejection fraction; NYHA, New York Heart Association; pEF, preserved ejection fraction; rEF, reduced ejection fraction.

Considering the different nosologies included in the study, the total population has been divided in population who manifested the composite event of all‐cause death and rehospitalization due to heart failure and patients who did not manifest the composite event.