TABLE 1.
Brain derived neurotrophic factor (BDNF) level at baseline and after 2 weeks of treatment.
| Variable | HC(n = 90) mean ± S.D. | ER (n = 41) mean ± S.D. | ENR (n = 48) mean ± S.D. | Analysis 1 | Analysis 2 | Analysis 3 | Analysis 4 | Analysis 5 | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| t | p | t | p | t | p | t | p | t | p | ||||
| Age in years | 29.79 ± 5.98 | 30.23 ± 6.89 | 29.35 ± 6.56 | −1.149 | 0.253 | −0.475 | 0.635 | ||||||
| BDNF level Baseline | 1552.04 ± 275.04 | 1188.50 ± 182.50 | 1095.51 ± 264.45 | 7.476 | <0.001** | 8.902 | <0.001** | 1.87 | 0.065 | ||||
| BDNF level 2 weeks later | 1335.99 ± 255.70 | 1169.41 ± 321.44 | 4.073 | <0.001** | 6.875 | <0.001** | 2.632 | 0.010* | −2.969 | 0.004** | −1.204 | 0.232 | |
Note: Analysis 1: ER group versus HC group; Analysis 2 ENR group versus HC group; Analysis 3 ER group versus ENR group; Analysis 4: ER group, 2 weeks later versus baseline; Analysis 5: ENR group, 2 weeks later versus baseline. The unit of measurement for BDNF:µg/L.
Abbreviations: ENR, early non‐response; ER, early response; HC, healthy control.
*p < 0.05, **p < 0.01.