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. 2023 Nov 22;6(4):805–827. doi: 10.20517/cdr.2023.77

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© The Author(s) 2023.

© The Author(s) 2023. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, sharing, adaptation, distribution and reproduction in any medium or format, for any purpose, even commercially, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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(A) Schematic illustration of the preparation and mechanism of self-motivated nanoparticles (SCC-NPs) in overcoming drug resistance; (B) ATP levels in HCT116/OxPt cells treated with Ctr NPs and SCC NPs at different doses; (C) The number of apoptotic cells treated with different formulations; (D) Cell viability of HCT116/OxPt cells after incubating with different treatments (^***P < 0.001). This figure is quoted with permission from Wang et al.^[139]. PEG: Poly (ethylene glycol).