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. 2023 Nov 22;6(4):805–827. doi: 10.20517/cdr.2023.77

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© The Author(s) 2023.

© The Author(s) 2023. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, sharing, adaptation, distribution and reproduction in any medium or format, for any purpose, even commercially, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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(A) Schematic illustration of supramolecular nanoparticle for inhibiting pump-mediated drug resistance; (B) Cell viability of HepG2/MDR1 cells treated with β-CD-g-(PEG-v-PNIPAAm)₇, PTX, and β-CD-g-(PEG-v-PNIPAAm)₇/PTX at different temperatures; (C) Changes in cell viability of HepG2/MDR1 cells treated with different doses of PTX and β-CD-g-(PEG-v-PNIPAAm)₇/PTX; (D) Tumor growth inhibition curves of tumor-bearing mice after various treatments (^*P < 0.05). This figure is quoted with permission from Fan et al.^[88]. CD: Cyclodextrin; MDR1: multidrug resistance gene; PEG: poly (ethylene glycol); PTX: paclitaxel.