TABLE 3.

Clinical Predictors for a Positive Genetic Test in the Derivation and the Validation Samples in the Final Predictive Model

	Derivation Sample			Validation Sample
	OR (95% CI)	Coefficient (95% CI)	P Value	OR (95% CI)	P Value
FH of DCM	2.29 (1.73–3.04)	0.83 (0.55–1.11)	<0.001	5.15 (3.80–6.97)	<0.001
Skeletal muscle disease	3.42 (1.60–7.31)	1.23 (0.47–1.99)	0.001	4.09 (1.23–13.62)	0.022
LBBB (absence of)	3.58 (2.57–5.01)	1.28 (0.94–1.61)	<0.001	2.79 (1.88–4.13)	<0.001
Low QRS voltage limb leads	3.61 (2.38–5.49)	1.28 (0.87–1.70)	<0.001	2.28 (1.48–3.52)	<0.001
Hypertension (absence of)	2.28 (1.67–3.13)	0.83 (0.51–1.14)	<0.001	2.09 (1.45–3.02)	<0.001
Intercept	0.07 (0.05–0.11)	−2.65 (−3.07/−2.24)	<0.001	0.04 (0.03–0.07)	<0.001

Abbreviations as in Table 1.