TABLE 4.

Characteristics of the Derivation and the Validation Samples

	Derivation Sample (n = 1,015)			Validation Sample (n = 1,097)
	Positive Genetic Test (n = 377)	Negative Genetic Test (n = 638)	P Value	Positive Genetic Test (n = 289)	Negative Genetic Test (n = 808)	P Value
Male	251 (66.58)	444 (69.59)	0.318	209 (72.32)	526 (65.10)	0.025
Age at diagnosis, y	48.15 ± 14.35	51.20 ± 14.47	<0.001	44.72 ± 15.50	51.03 ± 14.39	<0.001
Baseline LVEF	32.22 ± 10.42	31.96 ± 10.48	0.741	33.13 ± 11.16	32.59 ± 10.84	0.548
FH of DCM	231 (61.27)	249 (39.03)	<0.001	165 (57.09)	168 (20.79)	<0.001
Skeletal muscle disease	23 (6.10)	13 (2.04)	0.001	10 (3.46)	5 (0.62)	<0.001
Hypertension	85 (22.55)	255 (39.97)	<0.001	50 (17.30)	267 (33.04)	<0.001
Left bundle branch block	60 (15.92)	273(42.79)	<0.001	39 (13.49)	269 (33.29)	<0.001
Low QRS voltage limb leads	88 (23.34)	43 (6.74)	<0.001	48 (16.61)	68 (8.42)	<0.001

Values are n (%) or mean ± SD.

Abbreviations as in Table 1.