TABLE 3.
Model | Training cohort | Validation cohort | ||||
---|---|---|---|---|---|---|
AUC (95% CI) | SEN | SPE | AUC (95% CI) | SEN | SPE | |
RS-Ki-67 | 0.812 (0.710–0.914) | 0.667 | 0.846 | 0.799 (0.652–0.947) | 0.722 | 0.833 |
RS-HER-2 | 0.796 (0.686–0.906) | 0.720 | 0.776 | 0.705 (0.506–0.904) | 0.733 | 0.762 |
AUC, area under the ROC curve; CI, confidence interval; SEN, sensitivity; SPE, specificity; Ki-67, antigen identified by monoclonal antibody; HER-2, human epidermal growth factor receptor 2.