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. 2024 Jan 8;11:1220320. doi: 10.3389/fcell.2023.1220320

TABLE 3.

Performance of the developed RS-Ki-67 and RS-HER-2.

Model Training cohort Validation cohort
AUC (95% CI) SEN SPE AUC (95% CI) SEN SPE
RS-Ki-67 0.812 (0.710–0.914) 0.667 0.846 0.799 (0.652–0.947) 0.722 0.833
RS-HER-2 0.796 (0.686–0.906) 0.720 0.776 0.705 (0.506–0.904) 0.733 0.762

AUC, area under the ROC curve; CI, confidence interval; SEN, sensitivity; SPE, specificity; Ki-67, antigen identified by monoclonal antibody; HER-2, human epidermal growth factor receptor 2.