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. 2023 Oct 24;15(2):208–218. doi: 10.1111/jdi.14101

Table 3.

Predictive value of the metabolic syndrome, its components and insulin resistance for cardiovascular diseases

Cox models C statistic Integrated discrimination improvement Net reclassification index
Index 95% CI P value Index 95% CI P value Index 95% CI P value
Poor CVH status
MetS
Model 1 0.682 0.648–0.715 <0.001
Model 2 0.684 0.651–0.717 <0.001 0.006 0.004–0.007 <0.001 0.13 0.05–0.16 0.0154
High TG
Model 1 0.682 0.648–0.715 <0.001
Model 2 0.687 0.654–0.720 <0.001 0.004 0.003–0.006 <0.001 0.12 0.05–0.17 0.0140
Low HDL‐C
Model 1 0.682 0.648–0.715 <0.001
Model 2 0.686 0.653–0.719 <0.001 0.005 0.0001–0.008 0.042 0.09 0.05–0.16 0.0362
Abdominal obesity
Model 1 0.682 0.648–0.715 <0.001
Model 2 0.679 0.645–0.713 <0.001 0.005 −0.003 to 0.013 0.241 0.09 −0.19 to 0.18 0.1662
Insulin resistance
Model 1 0.682 0.648–0.715 <0.001
Model 2 0.696 0.647–0.744 <0.001 0.011 0.0002–0.021 0.045 0.11 0.06–0.18 0.04259
Intermediate CVH status
MetS
Model 1 0.759 0.742–0.775 <0.001
Model 2 0.760 0.744–0.777 <0.001 0.002 0.0007–0.004 0.005 0.14 0.10–0.21 0.03212
High TG
Model 1 0.759 0.742–0.775 <0.001
Model 2 0.759 0.743–0.776 <0.001 0.0006 −0.0004 to 0.001 0.265 0.07 −0.12 to 0.22 0.0862
Low HDL‐C
Model 1 0.759 0.742–0.775 <0.001
Model 2 0.760 0.744–0.776 <0.001 0.0007 0.0003–0.001 0.003 0.13 0.09–0.25 0.0123
Abdominal obesity
Model 1 0.759 0.742–0.775 <0.001
Model 2 0.756 0.739–0.772 <0.001 −0.0007 −0.003 to 0.002 0.612 0.09 −0.15 to 0.26 0.2652
Insulin resistance
Model 1 0.759 0.742–0.775 <0.001
Model 2 0.761 0.738–0.784 <0.001 0.0006 −0.001 to 0.002 0.478 0.10 −0.17 to 0.17 0.2159

Data were included for 3,433 participants.

HDL‐C, high density lipoprotein cholesterol; MetS, metabolic syndrome; TG, triglyceride.