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Number and percentage of substitutions per codon position of the reading frame +1. Non-structural (A) and structural (B) genes have shown separately. Note that codon position 1 (Pos 1) is the position 1 for frame +1 and position 2 for frame −2, position 2 (Pos 2) is the position 2 for frame +1 and position 1 for frame −2, and position 3 (Pos 3) is common to both frame +1 and −2 [see Fig. 1B(2) for more detail].
