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Activity-dependent synaptic plasticity in parallel, interacting circuits supports memory consolidation across three distinct but interacting locales: a temporal lobe memory stream; a medial diencephalic memory stream; and sites of cortico-cortical memory consolidation. Note, retrosplenial cortex also projects to the hippocampus, via the parahippocampal region. Diamonds indicate previously-observed sites of synaptic plasticity; other synapses remain to be comprehensively investigated.
