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. Author manuscript; available in PMC: 2024 Jan 23.
Published in final edited form as: Biol Psychiatry. 2023 Feb 9;94(8):630–639. doi: 10.1016/j.biopsych.2023.01.027

Table 3: Expression quantitative trait loci to MDD Wald Ratio MR Results.

These results indicate a positive causal effect of FADS1, FADS2, FADS3, MYRF and TMEM258 on lifetime MDD status. OR: Odds Ratio, CI: Confidence Intervals.

Gene SNV OR LOW CI
(95%)
HIGH CI
(95%)
MR_P
FADS1 rs174567 1.08 1.05 1.10 7.58x10−7
FADS2 rs968567 1.01 1.01 1.02 6.33x10−5
FADS3 rs2524288 1.05 1.01 1.10 0.010995
FEN1 rs10897119 0.98 0.89 1.07 0.617075
MYRF rs198462 1.03 1.01 1.05 0.000607
TMEM258 rs7943728 1.12 1.06 1.19 5.78x10−5