Fig 3.

Locations of shared iSNVs across the SARS-CoV-2 genome. Genome locations of shared iSNVs detected in unvaccinated (A) and vaccinated (B) participants. Number of dots at a locus indicates number of participants in which the shared iSNV was detected. Light gray dots indicate synonymous mutations, dark gray dots indicate nonsynonymous mutations, and white dots indicate UTR mutations. (C) Log(P-values) for shared iSNV counts within 100-nt genomic windows, based on a Poisson distribution derived from the average shared iSNV count for all genomic windows. Plot shows shared iSNV counts in unvaccinated individuals. Dashed line marks significance threshold of 1.68e-06. (D) Log(P-values) for shared iSNV counts within 100-nt genomic windows, in vaccinated individuals.