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. 2023 Jul 13;26(Suppl 2):e26107. doi: 10.1002/jia2.26107

Table 2.

Constructs of acceptability for injectable PrEP, adapted from the Theoretical Framework of Acceptability developed by Sekhon et al. [25]

Construct Operationalization Outcomes
Affective attitude Overall feelings about an intervention Satisfaction with, overall acceptability, liking or recommending injectable PrEP
Burden Perceived amount of effort to participate in the intervention Ease of use and facilitators; perceived challenges or concerns related to injectable PrEP
Ethicality Extent of fit with an individual's value system Discretion of product use; fitting with lifestyle preferences; perceived stigma
Intervention coherence Extent that participant understands the intervention/how it works Understanding how injectable PrEP prevents HIV
Opportunity costs Extent that benefits, profits or values must be given up to engage in the intervention Trade‐offs of taking injectable PrEP
Perceived effectiveness Perception that intervention is likely to achieve its purpose Degree of protection; perceived ability of injectable PrEP to prevent HIV
Self‐efficacy Participant's confidence that they can perform the behaviours required to participate in the intervention Ability to use/adhere to injectable PrEP; ability to regularly attend clinic visits to receive the injections

Abbreviation: PrEP, pre‐exposure prophylaxis.