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. 2023 Nov 6;28(1):e18029. doi: 10.1111/jcmm.18029

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© 2023 The Authors. Journal of Cellular and Molecular Medicine published by Foundation for Cellular and Molecular Medicine and John Wiley & Sons Ltd.

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Intratibial injection of MC4exo increased trabecular bone in the diaphysis. (A) Body weight and spleen weight at experimental endpoint. (B) Serum levels of TRAP‐5b, P1NP and CCL2. μCT analysis of the trabecular bone at 4 wks after intratibial injection with MC4exo or vehicle in the entire tibia (C) or diaphyseal region (D): tissue volume (TV), bone volume per total volume (BV/TV), trabecular thickness (Tb.Th), trabecular number (Tb.N), trabecular spacing (Tb.Sp) and bone mineral density (BMD). n = 12/group.