Table 1.
Characteristics | Mpox real-time polymerase chain reaction |
||||||
---|---|---|---|---|---|---|---|
Undetectable |
Detectable |
Total |
P-value | ||||
(n = 85; 21.6%) |
(n = 309; 78.4%) |
(n = 394; 100.0%) |
|||||
n | % | n | % | n | % | ||
Sex assigned at birth | <0.001 | ||||||
Male | 76 | 89.4 | 309 | 100.0 | 385 | 97.7 | |
Female | 9 | 10.6 | 0 | 0.0 | 9 | 2.3 | |
Age group (years old) | 0.01 | ||||||
≤ 24 | 12 | 14.1 | 22 | 7.1 | 34 | 8.6 | |
25 - 39 | 44 | 51.8 | 212 | 68.6 | 256 | 65.0 | |
≥ 40 | 29 | 34.1 | 75 | 24.3 | 104 | 26.4 | |
Race/Ethnicitya | 0.823 | ||||||
White | 49 | 57.6 | 164 | 53.1 | 213 | 54.1 | |
Black | 15 | 17.6 | 52 | 16.8 | 67 | 17.0 | |
Asian | 1 | 1.2 | 2 | 0.6 | 3 | 0.8 | |
Pardo (mixed) | 20 | 23.5 | 86 | 27.8 | 106 | 26.9 | |
Indigenous | 0 | 0.0 | 2 | 0.6 | 2 | 0.5 | |
Gender and sexual orientation | <0.001 | ||||||
Heterosexual | 16 | 18.8 | 4 | 1.3 | 20 | 5.1 | |
Man who have sex with men/ bisexual, or transgender woman | 69 | 81.2 | 305 | 98.7 | 374 | 94.9 | |
Years of studyb | 0.113 | ||||||
Up to 11 | 40 | 48.8 | 114 | 39.0 | 154 | 41.2 | |
12 or more | 42 | 51.2 | 178 | 61.0 | 220 | 58.8 | |
Patient category | 0.02 | ||||||
People living with HIV/AIDS | 52 | 61.2 | 168 | 54.4 | 220 | 58.8 | |
PrEP user | 15 | 17.6 | 99 | 32.0 | 114 | 28.9 | |
Non-HIV / Non-PrEP | 18 | 21.2 | 42 | 13.6 | 60 | 15.2 | |
Status according HIV infectionc | 0.371 | ||||||
VL < 50 copies/ml / CD4 < 350 cells/mm3 | 4 | 7.7 | 7 | 4.2 | 11 | 5.0 | |
VL < 50 copies/ml / CD4 ≥ 350 cells/mm3 | 36 | 69.2 | 136 | 81.0 | 172 | 78.2 | |
VL ≥ 50 copies/ml / CD4 < 350 cells/mm3 | 4 | 7.7 | 7 | 4.2 | 11 | 5.0 | |
VL ≥ 50 copies/ml / CD4 ≥ 350 cells/mm3 | 1 | 1.9 | 5 | 3.0 | 6 | 2.7 | |
Not available | 7 | 13.5 | 13 | 7.7 | 20 | 9.1 | |
Antiretroviral therapy usec | 0.457 | ||||||
No | 5 | 9.6 | 11 | 6.5 | 16 | 7.3 | |
Yes | 47 | 90.4 | 157 | 93.5 | 204 | 92.7 | |
Topography of lesions | 0.313 | ||||||
Cephalic/neck | 42 | 16.3 | 215 | 83.7 | 257 | 100.0 | |
Torso | 33 | 21.6 | 120 | 78.4 | 153 | 100.0 | |
Genitals/buttocks | 53 | 17.7 | 247 | 82.3 | 300 | 100.0 | |
Extremities | 36 | 22.6 | 123 | 77.4 | 159 | 100.0 | |
Number of segments affected | 0.238 | ||||||
One | 41 | 48.2 | 152 | 49.2 | 193 | 49.0 | |
Two | 26 | 30.6 | 73 | 23.6 | 99 | 25.1 | |
Three | 11 | 12.9 | 46 | 14.9 | 57 | 14.5 | |
Four | 5 | 5.9 | 36 | 11.7 | 41 | 10.4 | |
Ignored | 2 | 2.4 | 2 | 0.6 | 4 | 1.0 | |
Distribution of lesionsd | 0.006 | ||||||
Only genitals/buttocks | 27 | 32.5 | 128 | 41.7 | 155 | 39.7 | |
Genitals/buttocks and extra-genitals | 26 | 31.3 | 119 | 38.8 | 145 | 37.2 | |
Only extra-genitals | 30 | 36.1 | 60 | 19.5 | 90 | 23.1 | |
Morphology of lesions | 0.361 | ||||||
Macula | 27 | 21.8 | 97 | 78.2 | 124 | 100.0 | |
Papule | 40 | 19.4 | 166 | 80.6 | 206 | 100.0 | |
Vesicle | 11 | 22.0 | 39 | 78.0 | 50 | 100.0 | |
Pustule | 29 | 14.1 | 177 | 85.9 | 206 | 100.0 | |
Scab | 41 | 20.1 | 163 | 79.9 | 204 | 100.0 | |
Number of lesions | 0.596 | ||||||
Single | 12 | 14.1 | 37 | 12.0 | 49 | 12.4 | |
Multiple | 73 | 85.9 | 272 | 88.0 | 345 | 87.6 | |
Stage of lesions | 0.055 | ||||||
Single-phase | 31 | 36.5 | 80 | 25.9 | 111 | 28.2 | |
Polymorphic | 54 | 63.5 | 229 | 74.1 | 283 | 71.8 | |
Other signs and symptoms | 0.664 | ||||||
Adenomegaly | 28 | 10.7 | 233 | 89.3 | 261 | 100.0 | |
Fever | 16 | 8.5 | 172 | 91.5 | 188 | 100.0 | |
Headache | 20 | 10.9 | 163 | 89.1 | 183 | 100.0 | |
Myalgia | 22 | 12.8 | 150 | 87.2 | 172 | 100.0 | |
Asthenia | 22 | 13.2 | 145 | 86.8 | 167 | 100.0 | |
Back pain | 14 | 14.0 | 86 | 86.0 | 100 | 100.0 | |
Number of other signs and symptoms | <0.001 | ||||||
None | 32 | 37.6 | 24 | 7.8 | 56 | 14.2 | |
1 to 3 | 41 | 48.2 | 155 | 50.2 | 196 | 49.7 | |
4 or more | 12 | 14.1 | 130 | 42.1 | 142 | 36.0 | |
STI last 12 months | 0.144 | ||||||
No | 78 | 91,8 | 265 | 85.8 | 343 | 87.1 | |
Yes | 7 | 8.2 | 44 | 14.2 | 51 | 12.9 | |
Concurrent STI | 0.037 | ||||||
No | 74 | 87.1 | 290 | 93.9 | 364 | 92.4 | |
Yes | 11 | 12.9 | 19 | 6.1 | 30 | 7.6 | |
Number of sexual partnerse | 0.158 | ||||||
None | 7 | 10.1 | 16 | 6.5 | 23 | 7.3 | |
1 | 31 | 44.9 | 81 | 32.8 | 112 | 35.4 | |
2 to 5 | 20 | 29.0 | 107 | 43.3 | 127 | 40.2 | |
6 to 10 | 5 | 7.2 | 25 | 10.1 | 30 | 9.5 | |
11 or more | 6 | 8.7 | 18 | 7.3 | 24 | 7.6 | |
Presumed transmission route | 0.086 | ||||||
Sexual | 81 | 95.3 | 304 | 98.4 | 385 | 97.7 | |
Healthcare associated | 1 | 1.2 | 0 | 0.0 | 1 | 0.3 | |
Non-sexual contact | 3 | 3.5 | 5 | 1.6 | 8 | 2.0 |
PrEP: HIV pre-exposure prophylaxis; STI: sexually transmitted infection; VL: viral load.
Comparisons performed using chi-square tests. Bold indicates statistically significant difference (P <0.05).
Ignored for three patients
Ignored for 20 patients
Not applicable for 174 patients
Ignored for four patients
Ignored for 78 patients.