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. 2023 Nov 24;8(1):224–233. doi: 10.1182/bloodadvances.2023010813

Table 1.

Patient characteristics for each of the utilizer groups, presented as median (IQR) or frequency (%)

Commercial
Total
n = 5666
Low-utilizers
n = 2833
Moderate-utilizers
n = 1417
High-utilizers
n = 850
Super-utilizers
n = 566
Patient years 3.0 (2-5) 3.3 (2-5) 3.0 (2-5) 2.9 (1.8-4.5) 2.8 (1.7-4.1)
Age, y 32 (22-44) 34 (22-45) 32 (22-44) 31 (21-42) 28 (19-42)
Female 3389 (59.8%) 1672 (59.0%) 892 (62.9%) 505 (59.4%) 320 (56.5%)
Region
 Northeast 1115 (19.7%) 548 (19.3%) 275 (19.4%) 171 (20.1%) 121 (21.4%)
 North Central 751 (13.3%) 365 (12.9%) 200 (14.1%) 121 (14.2%) 65 (11.5%)
 South 3477 (61.4%) 1769 (62.4%) 863 (60.9%) 510 (60.0%) 335 (59.2%)
 West 307 (5.4%) 143 (5.0%) 75 (5.3%) 45 (5.3%) 44 (7.8%)
 Unknown 16 (0.3%) 8 (0.3%) 4 (0.3%) 3 (0.4%) 1 (0.2%)
SCD genotype
 Hb SS 2457 (43.4%) 797 (28.1%) 733 (51.7%) 530 (62.4%) 397 (70.1%)
 Hb SC 1179 (20.8%) 739 (26.1%) 268 (18.9%) 120 (14.1%) 52 (9.2%)
 Hb Sβ+/0 627 (11.1%) 343 (12.1%) 154 (10.9%) 83 (9.8%) 47 (8.3%)
 Nonspecific 1403 (24.8%) 954 (33.7%) 262 (18.5%) 117 (13.8%) 70 (12.4%)
CCI 0 (0-1) 0 (0-1) 0 (0-2) 1 (0-2) 2 (1-4)
SCD-related comorbidity
 CVD 624 (11.0%) 118 (4.2%) 170 (12.0%) 164 (19.3%) 172 (30.4%)
 CHF 543 (9.6%) 83 (2.9%) 129 (9.1%) 150 (17.6%) 181 (32.0%)
 PH 487 (8.6%) 98 (3.5%) 129 (9.1%) 133 (15.6%) 127 (22.4%)
 RD 536 (9.5%) 122 (4.3%) 123 (8.7%) 127 (14.9%) 164 (29.0%)
Medicare
Total
n = 8600
Low-utilizers
n = 4300
Moderate-utilizers
n = 2150
High-utilizers
n = 1290
Super-utilizers
n = 860
Patient years 4.5 (3.0-4.9) 4.5 (3.4-4.8) 4.7 (3.2-4.9) 4.6 (2.8-4.9) 3.2 (1.8-4.9)
Age, y 39 (29-53) 41 (30-56) 36 (28-51) 37 (28-51) 38 (28-52)
Female 4985 (58.0%) 2564 (59.6%) 1202 (55.9%) 742 (57.5%) 477 (55.5%)
Race
 White 401 (4.7%) 211 (4.9%) 93 (4.3%) 62 (4.8%) 35 (4.1%)
 Black 7621 (88.6%) 3808 (88.6%) 1903 (88.5%) 1140 (88.4%) 770 (89.5%)
 Other/unknown 578 (6.7%) 281 (6.5%) 154 (7.2%) 88 (6.8%) 55 (6.4%)
Region
 Midwest 1432 (16.7%) 742 (17.3%) 354 (16.5%) 192 (14.9%) 144 (16.7%)
 Northeast 1323 (15.4%) 653 (15.2%) 336 (15.6%) 215 (16.7%) 119 (13.8%)
 South 5159 (60.0%) 2575 (59.9%) 1269 (59.0%) 786 (60.9%) 529 (61.5%)
 West 686 (8.0%) 330 (7.7%) 191 (8.9%) 97 (7.5%) 68 (7.9%)
SCD genotype
 Hb SS 5590 (65.0%) 2407 (56.0%) 1577 (73.3%) 943 (73.1%) 663 (77.1%)
 Hb SC 928 (10.8%) 646 (15.0%) 165 (7.7%) 77 (6.0%) 40 (4.7%)
 HB Sβ+/0 643 (7.5%) 383 (8.9%) 133 (6.2%) 78 (6.0%) 49 (5.7%)
 Nonspecific 1439 (16.7%) 864 (20.1%) 275 (12.8%) 192 (14.9%) 108 (12.6%)
CCI 1 (0-3) 0 (0-1) 1 (0-3) 3 (1-5) 4 (2-6)
SCD-related comorbidity
 CVD 1232 (14.3%) 321 (7.5%) 366 (17.0%) 269 (20.9%) 276 (32.1%)
 CHF 2234 (26.0%) 485 (11.3%) 627 (29.2%) 602 (46.7%) 520 (60.5%)
 PH 1923 (22.4%) 397 (9.2%) 591 (27.5%) 514 (39.8%) 421 (49.0%)
 RD 2341 (27.2%) 564 (13.1%) 613 (28.5%) 635 (49.2%) 529 (61.5%)
Dual eligible 5552 (64.6%) 2504 (58.2%) 1497 (69.6%) 914 (70.9%) 637 (74.1%)

Low-utilizers: bottom 50% of costs; moderate-utilizers: top 25% to 49.9% of costs; high-utilizers: top 10% to 24.9% of costs; super-utilizers: top 10% of costs.

CHF, congestive heart failure; CVD, cerebrovascular disease; Hb SS: hemoglobin SS; Hb SC, hemoglobin SC; HB Sβ+/0, hemoglobin Sβ+/0 thalassemia; IQR, interquartile range; PH, pulmonary hypertension; RD, renal disease.