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. 2024 Jan 23;14:52. doi: 10.1038/s41398-024-02758-6

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — A Principal Component Analysis of LS clusters pseudo-bulked expression profiles across all samples. B Heatmap of genes enriched in group 1 (LS_In.C and LS_In.N), group 2 (LS_In.D, LS_In.M, LS_In.P, LS_In. Q, and LS_In.R) and previously calculated markers for LS_In.O, Sept_In.G, and Sept_In.I across our neuronal clusters. Normalized expression values (logcounts) centered and scaled. Violin plots of these genes expressed across LS populations for group 1 (C–F) and group 2 (G–J) highlight the specificity of these markers.