Table 4.

Treatment, follow-up and outcomes of patients with CHEK2-associated breast cancers

Surgical procedure
Partial mastectomya	11/35 (31%)
Total mastectomy	24/35 (69%)
Neoadjuvant therapy
Chemotherapy	14/35 (40%)
Hormone therapy	5/35 (14%)
Adjuvant therapy
Radiation	12/34 (35%)
Hormonal therapy	30/34 (88%)
Chemotherapy	13/34 (38%)
Patients with follow-up	34/35 (97%)
Mean follow-up, months (range)	50 (13–183)
Local recurrence	1/34 (3%)
Distant metastasis	5/34 (15%)
Disease status
No evidence of disease	29/34 (85%)
Alive with disease	4/34 (12%)
Died of disease	1/34 (3%)

^aOne patient underwent completion mastectomy after 1 year