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. 2024 Jan 10;14:1333447. doi: 10.3389/fphar.2023.1333447

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Copyright © 2024 Haq, Qayoom, Sofi, Jan, Shabir, Ahmad, Ahmad, Almilaibary and Mir.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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PredictProtein database was used to employ and analyze the general protein sequence of P53 and the effect of point mutations responsible for the misfolding of P53 protein possessing disordered sites aiding to its aggressiveness.