TABLE 1.
ADMET analysis.
| S. No. | Compound PubChem CID | Molecular weight g/mol | TPSA Å2 | GI absorption | Lipinski’s Rule | Ghose rule | Veber rule | Egan rule | Muegge’s rule | ADMET screening |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 16255105 | 274.79 | 16.96 | High | Yes | Yes | Yes | Yes | Yes | Yes |
| 2 | 407362 | 315.43 | 7.94 | High | Yes | Yes | Yes | Yes | Yes | Yes |
| 3 | 401966 | 317.39 | 53.71 | High | Yes | Yes | Yes | Yes | Yes | Yes |
| 4 | 364676 | 298.81 | 16.96 | High | Yes | Yes | Yes | Yes | Yes | Yes |
| 5 | 53389 | 321.46 | 20.20 | High | Yes | Yes | Yes | Yes | Yes | Yes |
| 6 | 5072 | 321.46 | 20.20 | High | Yes | Yes | Yes | Yes | Yes | Yes |
| 7 | 31061 | 304.43 | 17.82 | High | Yes | Yes | Yes | Yes | Yes | Yes |
| 8 | 42404 | 290.40 | 16.96 | High | Yes | Yes | Yes | Yes | Yes | Yes |
| 9 | 49539 | 292.42 | 8.17 | High | Yes | Yes | Yes | Yes | Yes | Yes |
| 10 | 301801 | 262.35 | 17.29 | High | Yes | Yes | Yes | Yes | Yes | Yes |