| What is the burden and risk of long-term sequelae of COVID-19 in PWH? |
| Are innate immune responses targeting SARS-CoV-2 compromised in PWH? |
| Do robust mucosal responses and tissue resident memory develop at relevant sites in PWH? |
| What is the magnitude and quality of vaccine-induced immune responses in PWH with low CD4 count and/or elevated HIV viral load? |
| How durable are immune responses after infection and/or vaccination in PWH? |
| What is the impact of HIV infection on SARS-CoV-2-specific follicular helper T cells after vaccination and/or infection? |
| What are the mechanisms of viral persistence in PWH who are immunocompetent? |
| Does T-cell escape emerge in prolonged SARS-CoV-2 infection in PWH? |
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