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Schematic overview of the study. (A) Overview of the patient cohort and sample set included in the respiratory metagenomics (RMg) pilot service. (B) The metagenomics regimen that was followed on a daily basis when samples were requested for RMg service. Steps outlined include sample collection until reporting results to ICU physicians. (C) Respiratory metagenomic end-to-end clinical pathway. LRT = lower respiratory tract; MV = mechanically ventilated; QC = quality control.
