Table 3.

Comparison between patients with higher and lower RV Dyssynchrony Index (RVDI)

	Patients with RVDI<median N=113	Patients with RVDI≥median N=109	P value
Clinical characteristics
Age at repair—years	5.7 (1–9)	4.7 (1–6)	0.35
Age at baseline—years	33±12	34±13	0.45
Primary repair	73 (65%)	71 (65%)	0.9
NYHA functional class I	94 (83%)	93 (85%)	0.8
NT-proBNP—pg/mL	119 (57–983)	153 (70–1666)	0.3
No device (ICD, PM, CRT)	104 (92%)	98 (89%)	0.7
QRS duration—ms	143±25	144±27	0.91
Adverse clinical events	10 (9%)	14 (13%)	0.3
Echocardiography data
LVEDD—mm	46±6	48±7	0.008
LVESD—mm	30±5	33±7	0.001
LVEF—%	60±8	58±8	0.05
LAVI—mL/m2	24±10	29±17	0.04
RA area—cm2	19±7	20±7	0.12
RV-RA gradient—mm Hg	32±12	30±12	0.21
Severe tricuspid regurgitation	2 (1.8%)	1 (0.6%)	0.147
Severe pulmonary regurgitation	16 (14.5%)	43 (24.5%)	0.023
RV FAC—%	38±7	39±9	0.4
RV GLS—%	−16±4.4	−14.6±5	0.032
IVSD—ms	86±38	126±56	<0.001
IVED—ms	−4.5±15.9	−1.6±21.9	0.3
CMR data
LV EDVI—mL	83±17	90±23	0.007
RV EDVI—mL	122±28	137±19	0.004
RV EF—%	47±8	47±8	0.8
LV EF—%	60±8	57±9	0.02
Exercise data
Peak VO2—mL/kg/min	21±9	21±9	0.9
Peak heart rate—bpm	159±30	158±26	0.7
VE/VCO2	26±5	27±5	0.6

Data are expressed as N (% of total), mean±SD or median (IQR) unless otherwise specified.

CMR, cardiac MR; CRT, cardiac resynchronization therapy; EDVI, end-diastolic volume indexed; FAC, fractional area change; GLS, global longitudinal strain; ICD, Implantable cardioverter-defibrillator; IVED, interventricular ejection delay; IVSD, interventricular shortening delay; LAVI, left atrial volume indexed; LVEDD, left ventricular end-diastolic diameter; LVEF, left ventricular ejection fraction; LVESD, left ventricular end-systolic diameter; NYHA, New York Heart Association; PM, pacemaker; RV EDV, right ventricular end-diastolic volume; RVEF, right ventricular ejection fraction; VE/VCO₂, minute ventilation/carbon dioxide output; VO₂, oxygen uptake.