Table 4.

Comparison of the baseline characteristics between patients with and without event

	Patients without event N=252 (88%)	Patients with event N=33 (12%)	P value
Clinical characteristics
Age at repair—years	2.6 (2.2–35.6)	6.2 (2.2–29.9)	0.023
Age at baseline—years	29.3 (22.2–65.8)	47.5 (33.1–67.5)	<0.001
Primary repair	172 (68)	14 (42)	0.003
NYHA functional class I	210 (83)	19 (58)	0.001
NT-proBNP—pg/mL	120 (59–983)	434 (191–1871)	<0.001
No device (ICD, PM, CRT)	236 (94)	27 (82)	0.011
QRS duration—ms	142±25	156±27	0.004
Echocardiography data
LVEDD—mm	46±6	50±8	0.016
LVESD—mm	31±6	35±9	0.012
LVEF—%	59±8	57±11	0.31
LAVI—mL/m2	24±11	38±21	0.004
RA area—cm2	18±6	25±6	<0.001
RV-RA gradient—mm Hg	30±12	39±10	<0.001
RV FAC—%	39±8	35±11	0.03
Severe tricuspid regurgitation	1 (0.4%)	2 (6.3%)	0.002
Severe pulmonary regurgitation	47 (18%)	12 (36%)	0.014
RV GLS—%	−16±5	−15±6	0.38
RV Dyssynchrony Index—ms	49±31	41±18	0.21
IVSD—ms	103±50	130±65	0.09
IVED—ms	−3.3±19	2.5±19	0.12
CMR data
LV EDVI—mL	86±19	99±31	0.99
RV EDVI—mL	124±31	139±56	0.95
RV EF—%	43±13	48±8	0.11
LV EF—%	57±7	53±11	0.02
Exercise data
Peak VO2—mL/kg/min	22±9	18±11	0.03
Peak heart rate—bpm	161±24	133±33	0.003
VE/VCO2	26±5	30±5	<0.001

Data are expressed as N (% of total), mean±SD or median (IQR) unless otherwise specified.

CMR, cardiac MR; CRT, cardiac resynchronization therapy; EDVI, end-diastolic volume indexed; RV FAC, right ventricular fractional area change; GLS, global longitudinal strain; ICD, Implantable cardioverter-defibrillator; IVED, interventricular ejection delay; IVSD, interventricular shortening delay; LAVI, left atrial volume indexed; LVEDD, left ventricular end-diastolic diameter; LVEF, left ventricular ejection fraction; LVESD, left ventricular end-systolic diameter; NT-proBNP, N-terminal pro–B-type natriuretic peptide; NYHA, New York Heart Association; PM, pacemaker; RV EDV, right ventricular end-diastolic volume; RVEF, right ventricular ejection fraction; VE/VCO₂, minute ventilation/carbon dioxide output; VO₂, oxygen uptake.