TABLE 1.
Demographic, neuropsychological, and behavioral variables for the diagnostic groups and total sample.
| Variable | CN | EOAD | EOnonAD | Total sample |
|---|---|---|---|---|
| N | 82 | 166 | 62 | 310 |
| Age (years)a | 55.63 (6.0) | 58.82 (3.9) | 57.45 (6.2) | 57.70(5.2) |
| Education (years)a,b | 16.84 (2.1) | 15.36(2.4) | 15.69 (2.6) | 15.82 (2.5) |
| Sex(%female)b,c | 61.0% | 54.8% | 35.5% | 52.6% |
| Race (% Caucasian)a,b | 68.5% | 92.3% | 89.2% | 85.1% |
| Geriatric Depression Scalea,b | 1.35 (1.8) | 2.49 (2.3) | 3.03 (2.6) | 2.28 (2.3) |
| Barona estimate of verbal intelligence | 107.36 (5.3) | 105.85 (6.4) | 106.07 (6.7) | 106.31 (6.2) |
| MoCAa,b,c | 27.12(2.5) | 16.53(5.5) | 21.54 (5.0) | 20.35 (6.6) |
| RAVLTTotal Recalla,b,c | 48.44 (8.3) | 22.08 (9.4) | 34.71 (11.8) | 31.58(14.8) |
| RAVLT Delayed Recalla,b,c | 9.90 (3.2) | 1.64 (2.3) | 4.90 (4.0) | 4.47 (4.5) |
| Craft Story 21 Recalla,b,c | 15.17(5.4) | 6.86 (4.3) | 11.32 (4.8) | 10.06 (5.9) |
| Craft Story 21 Recall Delayea,b,c | 14.73 (5.2) | 4.42 (4.4) | 9.60 (5.4) | 8.36 (6.6) |
| Benson Delayed Recala,b,c | 12.16(2.6) | 3.64 (3.7) | 9.09 (4.0) | 7.21 (5.2) |
| ADAS-Cog Total Scora,b,c | 17.97 (3.6) | 34.68 (8.5) | 26.65 (7.3) | 28.67(10.1) |
| ADAS-Cog Word Recall Immediate Recala,b,c | 22.36 (3.5) | 10.88 (4.7) | 16.34 (4.5) | 15.00(6.6) |
| ADAS-Cog Word Recall Delayed Recala,b,c | 7.70 (1.7) | 1.95(2.1) | 4.64 (2.4) | 4.03 (3.2) |
Note: Barona Estimate ofVerbal Intelligence score is listed as a standard score. All other scores are rawscores. All values are mean (standard deviation) unless listed otherwise.
Abbreviations: ADAS-Cog, Alzheimer’s Disease Assessment Scale-Cognitive subscale; CN, cognitively normal; EOAD, early-onset Alzheimer’s disease; EOnonAD, early-onset non-Alzheimer’s disease; MoCA, Montreal Cognitive Assessment; RAVLT, Rey Auditory Verbal Learning Test.
a
Denotes significant difference between CN and EOAD groups.
b
Denotes significant difference between CN and EOnonAD groups.
c
Denotes significant difference between EOAD and EOnonAD groups.