TABLE 3.
Partial correlation coefficients between Rey Auditory Verbal Learning Test learning slope/process scores and neuropsychological test scores across diagnostic groups and the total sample, after controlling for age, education, sex, and ethnicity.
| Variable | Correlated with | CN | EOAD | EOnonAD | Total sample |
|---|---|---|---|---|---|
| N | 82 | 168 | 64 | 314 | |
| RAVLT LR | RAVLTTotal Recall | 0.73, P < 0.001 | 0.69, P < 0.001 | 0.82, P < 0.001 | 0.87, P < 0.001 |
| RAVLT Delayed Recall | 0.64, P < 0.001 | 0.66, P < 0.001 | 0.90, P < 0.001 | 0.87, P < 0.001 | |
| ADAS-Cog Word Recall Immediate Recall | 0.25, P = 0.03 | 0.44, P < 0.001 | 0.50, P < 0.001 | 0.70, P < 0.001 | |
| ADAS-Cog Word Recall Delayed Recall | 0.34, P = 0.003 | 0.57, P < 0.001 | 0.67, P < 0.001 | 0.78, P < 0.001 | |
| CraftStory 21 Recall Immediate | 0.10, P = 0.39 | 0.33, P < 0.001 | 0.56, P < 0.001 | 0.57, P < 0.001 | |
| CraftStory 21 Recall Delayed | 0.11, P = 0.37 | 0.42, P < 0.001 | 0.66, P < 0.001 | 0.66, P < 0.001 | |
| Benson Delayed Recall | 0.08, P = 0.50 | 0.52, P < 0.001 | 0.47, P < 0.001 | 0.69, P < 0.001 | |
| Semantic Fluency | 0.02, P = 0.87 | 0.31, P < 0.001 | 0.59, P < 0.001 | 0.58, P < 0.001 | |
| Multilingual Naming Test | −0.02, P = 0.90 | 0.17, P < 0.001 | 0.35, P < 0.001 | 0.33, P < 0.001 | |
| Trail Making Test, Part B | −0.11, P = 0.36 | −0.26, P < 0.001 | −0.45, P < 0.001 | −0.59, P < 0.001 | |
| RAVLT RLS | RAVLTTotal Recall | 0.22, P = 0.06 | 0.49, P < 0.001 | 0.51, P < 0.001 | 0.65, P < 0.001 |
| RAVLT Delayed Recall | 0.31, P = 0.007 | 0.53, P < 0.001 | 0.72, P < 0.001 | 0.71, P < 0.001 | |
| ADAS-Cog Word Recall Immediate Recall | −0.04, P = 0.72 | 0.33, P < 0.001 | 0.33, P = 0.01 | 0.54, P < 0.001 | |
| ADAS-Cog Word Recall Delayed Recall | 0.13, P = 0.27 | 0.49, P < 0.001 | 0.56, P < 0.001 | 0.65, P < 0.001 | |
| CraftStory 21 Recall Immediate | −0.09, P = 0.43 | 0.26, P = 0.002 | 0.45, P < 0.001 | 0.45, P < 0.001 | |
| CraftStory 21 Recall Delayed | −0.13, P = 0.25 | 0.36, P < 0.001 | 0.58, P < 0.001 | 0.54, P < 0.001 | |
| Benson Delayed Recall | −0.04, P = 0.75 | 0.47, P < 0.001 | 0.46, P < 0.001 | 0.60, P < 0.001 | |
| RAVLT LOT | RAVLTTotal Recall | 0.39, P < 0.001 | 0.48, P < 0.001 | 0.57, P < 0.001 | 0.68, P < 0.001 |
| RAVLT Delayed Recall | 0.40, P < 0.001 | 0.52, P < 0.001 | 0.69, P < 0.001 | 0.72, P < 0.001 | |
| ADAS-Cog Word Recall Immediate Recall | 0.05, P = 0.64 | 0.35, P < 0.001 | 0.31, P = 0.02 | 0.56, P < 0.001 | |
| ADAS-Cog Word Recall Delayed Recall | 0.27, P = 0.02 | 0.48, P < 0.001 | 0.56, P < 0.001 | 0.67, P < 0.001 | |
| CraftStory 21 Recall Immediate | −0.01, P = 0.94 | 0.29, P < 0.001 | 0.43, P = 0.001 | 0.46, P < 0.001 | |
| CraftStory 21 Recall Delayed | −0.05, P = 0.65 | 0.36, P < 0.001 | 0.58, P < 0.001 | 0.54, P < 0.001 | |
| Benson Delayed Recall | 0.00, P = 0.99 | 0.42, P < 0.001 | 0.49, P < 0.001 | 0.58, P < 0.001 | |
| RAVLT trial 1 | RAVLTTotal Recall | 0.63, P < 0.001 | 0.78, P < 0.001 | 0.74, P < 0.001 | 0.82, P < 0.001 |
| RAVLT Delayed Recall | 0.37, P < 0.001 | 0.35, P < 0.001 | 0.43, P < 0.001 | 0.60, P < 0.001 | |
| ADAS-Cog Word Recall Immediate Recall | 0.40, P < 0.001 | 0.50, P < 0.001 | 0.43, P < 0.001 | 0.65, P < 0.001 | |
| ADAS-Cog Word Recall Delayed Recall | 0.24, P = 0.04 | 0.30, P < 0.001 | 0.29, P = 0.03 | 0.55, P < 0.001 | |
| CraftStory 21 Recall Immediate | 0.26, P = 0.02 | 0.32, P < 0.001 | 0.30, P = 0.03 | 0.48, P < 0.001 | |
| CraftStory 21 Recall Delayed | 0.32, P = 0.005 | 0.26, P = 0.002 | 0.21, P = 0.12 | 0.49, P < 0.001 | |
| Benson Delayed Recall | 0.15, P = 0.20 | 0.19, P = 0.03 | 0.14, P = 0.35 | 0.47, P < 0.001 |
Note: Values reflect partial correlation coefficients and resultant P-value.
Abbreviations: ADAS-Cog, Alzheimer’s Disease Assessment Scale-Cognitive subscale; CN, cognitively normal; EOAD, early-onset Alzheimer’s disease; EOnonAD, early-onset non-Alzheimer’s disease; LOT, learning over trials; LR, learning ratio; RAVLT, Rey Auditory Verbal Learning Test; RLS, raw learning score.