Table 5.

Multivariate associations between the change in the medication appropriateness* throughout the 12 month follow-up period and patients’ attitudes towards deprescribing † (n=242)

Name of the variable	Coefficient	P value	95% CI
rPATD global question: ‘If my doctor said it was possible, I would be willing to stop one or more of my regular medicines’ (reference: strongly agree)
Agree	0.35	0.426	−0.51 to 1.21
Unsure	0.92	0.293	−0.79 to 2.63
Disagree	−1.01	0.145	−2.36 to 0.35
Strongly disagree	−0.80	0.221	−2.08 to 0.48
Alternative measurements of patients’ willingness to have medications deprescribed based on the rPATD
Concerns about stopping score (per 1-unit increase)*
	−0.29	0.120	−0.65 to 0.08
‘I would like to try stopping one of my medicines to see how I feel without it’ (reference: strongly agree)
Agree	−0.45	0.253	−1.21 to 0.32
Unsure	−0.66	0.281	−1.87 to 0.54
Disagree	−0.45	0.246	−1.22 to 0.31
Strongly disagree	−0.57	0.233	−1.51 to 0.37
‘I would like my doctor to reduce the dose of one or more of my medicines’ (reference: strongly agree)
Agree	−0.44	0.253	−1.20 to 0.32
Unsure	−0.59	0.282	−1.67 to 0.49
Disagree	−0.02	0.968	−0.95 to 0.99
Strongly disagree	0.13	0.795	−0.85 to 1.11

Multilevel linear regression models adjusted for patient age, education status, gender, number of chronic conditions, living situation, whether the patient is housebound or not, patient satisfaction with medications, the number of GP consultations in the 6 months prior to the study inclusion, and the group allocation during the trial. Missingness: The change in the Medication Appropriateness Index over the 12 month follow-up period had 13% missing values.

*As assessed using the Medication Appropriateness Index: Samsa et al²⁶ 1994.

†As calculated based on Reeve et al¹⁶ 2016.

rPATD, revised Patient Attitudes Towards Deprescribing.