Table 4.
Clinical characteristics of hospitalised COVID-19 cases in CPRD Aurum-HES linked data, by high-risk definitions
| All (n=13 165) | Meeting NHS highest risk conditions (n=4333) | Meeting PANORAMIC criteria (n=11 011) | Meeting UKHSA clinical risk (n=5353) | |
| Hospitalised cases meeting definition | -- | 33% | 84% | 41% |
| Smoking status | ||||
| Current smoker | 1690 (13%) | 655 (15%) | 1476 (13%) | 840 (16%) |
| Former smoker | 3810 (29%) | 1574 (36%) | 3544 (32%) | 2070 (39%) |
| Never smoked | 4205 (32%) | 1362 (31%) | 3513 (32%) | 1746 (33%) |
| Unknown | 3460 (26%) | 742 (17%) | 2478 (23%) | 697 (13%) |
| Body mass index (kg/m2) | ||||
| Mean (SD) | 31.9 (7.5) | 31.4 (7.5) | 31.7 (7.4) | 31.4 (7.7) |
| Underweight (<18.5) | 96 (1%) | 51 (1%) | 90 (1%) | 70 (1%) |
| Not overweight (18.5–24.9) | 1162 (9%) | 509 (12%) | 1060 (10%) | 729 (14%) |
| Overweight (25.0–29.9) | 2390 (18%) | 949 (22%) | 2161 (20%) | 1239 (23%) |
| Obese (≥30.0) | 4586 (35%) | 1662 (38%) | 4053 (37%) | 2231 (42%) |
| Unknown | 4931 (37%) | 1162 (27%) | 3647 (33%) | 1084 (20%) |
| Charlson Comorbidity Index | ||||
| Mean (SD) | 1.0 (1.6) | 1.9 (2.1) | 1.2 (1.7) | 2.0 (2.0) |
| 0 | 7128 (54%) | 1283 (30%) | 5158 (47%) | 894 (17%) |
| 1 or 2 | 4241 (32%) | 1833 (43%) | 4094 (37%) | 2.927 (55%) |
| 3 or 4 | 1161 (9%) | 711 (16%) | 1129 (10%) | 963 (18%) |
| 5+ | 635 (5%) | 506 (12%) | 630 (6%) | 569 (11%) |
CPRD, Clinical Practice Research Datalink; HES, Hospital Episode Statistics; NHS, National Health Service; PANORAMIC, Platform Adaptive trial of NOvel antiviRals for eArly treatMent of COVID-19 In the Community; UKHSA, UK Health Security Agency.