TABLE 2.
Summary of PA103 and mutant phenotypes
Strain | Invasiveness | Cytotoxicitya | Putative type III proteins secreted | Similarity of sequence at Tn5 insertion sitea | Postulated delivery to host cell of Putative AIFb |
---|---|---|---|---|---|
PA103 | No | Yes | PepA, PepB, PepD, ExoT | + | |
Mutant 16 | Yes | No | Not tested | − | |
Mutant M | Yes | No | yscN | − | |
Mutant N | Yes | No | pscJ, yscJ | − | |
Mutant P | Yes | No | PepA, PepB, PepD, ExoT (variable amounts) | Not tested | +/− |
Mutant Q | Yes | No | Not tested | − | |
Mutant 1 | Yes | No | PepA, ExoT | None | − |
Mutant 8 | No | Minimal | PepB, PepD, ExoT | pepA/exoU | + |
Mutant 13 | No | Minimal | PepB, PepD, ExoT, truncated PepA | pepA/exoU | + |