Table 2.
Anchor-based
WPMI estimates |
Distribution-based estimates | Reliabilityi | ||||||||
---|---|---|---|---|---|---|---|---|---|---|
Anchor | N | Mean | 95% CI | SRM | Sensitivity | Specificity | 0.5 SD | RCI(80) | ||
SF-36v2 scale (0–100 scoring) | ||||||||||
PF | PtGAa | 120 | 24.5 | 21.1, 28.0 | 1.27 | 0.78 | 0.56 | 9.8 | 12.7 | 0.87 |
RP | PtGAa | 120 | 24.5 | 20.6, 28.5 | 1.37 | 0.77 | 0.58 | 9.1 | 10.7 | 0.89 |
BP | PtGAa | 120 | 25.4 | 21.9, 28.9 | 1.65 | 0.80 | 0.43 | 7.6 | 11.1 | 0.84 |
PAINb | 125 | 26.6 | 23.3, 29.9 | 1.73 | 0.87 | 0.47 | ||||
GH | PtGAa | 120 | 13.6 | 10.8, 16.4 | 0.87 | 0.74 | 0.45 | 8.2 | 16.7 | 0.68 |
VT | PtGAa | 120 | 21.5 | 18.2, 24.8 | 1.30 | 0.75 | 0.50 | 8.3 | 13.1 | 0.81 |
AN5c | 60 | 23.3 | 18.7, 28.0 | 1.41 | 0.71 | 0.55 | ||||
SF | PtGAa | 120 | 20.5 | 16.3, 24.7 | 0.98 | 0.66 | 0.51 | 10.5 | 19.7 | 0.74 |
RE | PtGAa | 120 | 16.9 | 12.9, 21.0 | 0.70 | 0.68 | 0.45 | 12.4 | 12.1 | 0.93 |
MH | PtGAa | 120 | 14.3 | 11.3, 17.3 | 0.75 | 0.69 | 0.53 | 9.5 | 13.3 | 0.85 |
SF-36v2 summary (NBS scoring) | ||||||||||
PCS | PtGAa | 120 | 9.7 | 8.3, 11.1 | 1.47 | 0.83 | 0.47 | 3.4 | 4.1 | 0.89 |
MCS | PtGAa | 120 | 7.6 | 5.8, 9.4 | 0.70 | 0.66 | 0.50 | 5.4 | 6.0 | 0.91 |
FACIT-Fatigue (0–52 scoring) | ||||||||||
Fatigue | SF-36 PGISd | 120 | 11.3 | 9.7, 12.9 | 1.15 | 0.81 | 0.52 | 0.92 | ||
PtGAa | 80 | 9.7 | 8.1, 11.4 | 0.99 | 0.75 | 0.58 | 4.9 | 4.9 | ||
VT03e | 74 | 11.1 | 9.4, 12.9 | 1.13 | 0.85 | 0.55 | ||||
RASIQ (0–100 scoring) | ||||||||||
Joint pain | SF-36 PGISd | 66 | -24.0 | -28.4, -19.7 | -1.34 | 0.73 | 0.56 | 9.1 | -6.8 | 0.96 |
PtGAa | 104 | -31.0 | -34.6, -27.5 | -1.70 | 0.94 | 0.49 | ||||
PAINb | 97 | -32.7 | -36.2, -29.3 | -1.80 | 0.94 | 0.51 | ||||
BP01f | 71 | -21.7 | -25.4, -18.0 | -1.21 | 0.84 | 0.58 | ||||
Joint stiffness | PGISd | 66 | -23.3 | -27.4, -19.1 | -1.31 | 0.73 | 0.62 | 9.1 | -13.1 | 0.84 |
PtGAa | 104 | -26.1 | -29.8, -22.3 | -1.44 | 0.83 | 0.47 | ||||
Impact | SF-36 PGISd | 66 | -21.0 | -24.5, -17.4 | -1.35 | 0.89 | 0.48 | 7.8 | -12.8 | 0.80 |
PtGAa | 104 | -21.1 | -24.3, -17.9 | -1.35 | 0.93 | 0.44 | ||||
AN2g | 70 | -17.4 | -20.7, -14.0 | -1.12 | 0.85 | 0.57 | ||||
AN1h | 61 | -17.8 | -21.7, -13.8 | -1.14 | 0.79 | 0.58 |
a‘Considering all the ways your arthritis has affected you, how active do you feel your arthritis is…’. Improvement: a decline of 18 points or more
b‘How much pain are you currently having because of your rheumatoid arthritis?’ Improvement: a decline of 20 points or more
c‘I have energy’. Improvement: an increase of 1 point on a 5-point Likert scale
d‘In general, would you say your health is…’. Improvement: an increase of 1 point on a 5-point Likert scale
e‘How much of the time during the past 4 weeks did you feel worn out?’ Improvement: an increase of 1 point on a 5-point Likert scale
f‘How much bodily pain have you had during the past 4 weeks?’ Improvement: an increase of 1 point on a 5-point Likert scale
g‘I feel tired’. Improvement: an increase of 1 point on a 5-point Likert scale
h‘I feel listless (washed out)’. Improvement: an increase of 1 point on a 5-point Likert scale
iCronbach’s alpha, except for SF-36v2 summary scores (PCS, MCS), where reliability is estimated using a method that accounts for the reliability of each score as well as covariances among the scores
AN: anchor; BP, bodily pain; CI: confidence interval; FACIT-Fatigue: Functional Assessment of Chronic Illness Therapy-Fatigue; GH: general health perceptions; MCS: Mental Component Summary; MH: role limitations due to emotional problems; PAIN: Patient’s Assessment of Arthritis Pain; PCS: Physical Component Summary; PF: physical functioning; PGIS: Patient’s Global Impression of Status; PtGA: Patient’s Global Assessment of Disease Activity; RASIQ: Rheumatoid Arthritis Symptoms and Impact Questionnaire; RCI(80): reliable change index based on 80% confidence interval; RE: role limitations due to emotional problems; RP: role limitations due to physical health; SD: standard deviation; SF: social functioning; SF-36v2: Short-Form 36 Health Survey version 2; SRM: standardized response mean; VT: vitality; WPMI: within-patient meaningful improvement