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. Author manuscript; available in PMC: 2024 Nov 1.
Published in final edited form as: Alzheimers Dement. 2023 Sep 10;19(Suppl 9):S98–S114. doi: 10.1002/alz.13453

FIGURE 4.

FIGURE 4

Regional distribution of amyloid- and tau-PET signal in the EOAD group. Regional distribution of amyloid- (A) and tau (B)-PET signal in all groups. Mean SUVR values were extracted from 68 cortical ROIs from the Desikan-Killiany atlas. The right panel shows group differences between EOAD and CN groups, quantified as Cohen’s d effect sizes (all 68 ROIs are different with Bonferroni-corrected p < 0.05). All pairwise group comparisons are described in detail in Table S1. CN, cognitively normal; EOAD, early-onset Alzheimer’s disease; PET, positron emission tomography; ROI, region of interest; SUVR, standardized uptake value ratio