Table 3.

Toxicity summary for treatment-related toxicities

Category	Adverse event	All grades Number of patients (%)	Grades 3–4 Number of patients (%)
Cardiac	Prolonged QTc	8 (40)	0 (0)
Gastrointestinal	Anorexia	12 (60)	0 (0)
	Abdominal pain	4 (20)	0 (0)
	Diarrhea	16 (80)	3 (15)
	Mucositis	4 (20)	1 (5)
	Nausea	16 (80)	1 (5)
	Vomiting	12 (60)	1 (5)
General	Fatigue	10 (50)	3 (15)
Hematologic	White blood cell decreased	4 (20)	4 (20)
Investigations	Weight loss	9 (45)	0 (0)
Metabolic	Dehydration	9 (45)	1 (5)
Musculoskeletal	Generalized muscle weakness	6 (30)	0 (0)
Neurologic	Dizziness	4 (20)	0 (0)
	Dysgeusia	10 (50)	0 (0)
Vascular	Flushing	4 (20)	0 (0)

Includes toxicities with at least 20% incidence