Table 4.

All (related and unrelated) cardiac adverse events

Adverse event	All grades Number of patients (%)	Grades 3–4 Number of patients (%)
Atrial fibrillation	2 (10)	1 (5)
Atrial flutter	1 (5)	0 (0)
Cardiac arrest	2 (10)	2 (10)
Non-specific ST and/or T wave changes	3 (15)	0 (0)
Cardiac troponin I increased	2 (10)	2 (10)
Cardiac troponin T increased	1 (5)	1 (5)
Chest pain, cardiac	2 (10)	1 (5)
Conduction disorder	1 (5)	0 (0)
Electrocardiogram QTc prolonged	17 (85)	2 (10)
Myocardial infarction	1 (5)	1 (5)
Pericardial effusion	1 (5)	0 (0)
Pericarditis	1 (5)	0 (0)
Sinus bradycardia	2 (10)	0 (0)
Sinus tachycardia	11 (55)	0 (0)
Ejection fraction decreased	1 (5)	0 (0)
Acute coronary syndrome	1 (5)	0 (0)
Pericardial tamponade	1 (5)	1 (5)