. Author manuscript; available in PMC: 2024 Jan 24.

Published in final edited form as: Aliment Pharmacol Ther. 2023 Nov 15;59(1):80–88. doi: 10.1111/apt.17783

TABLE 3.

Factors associated with the composite outcome (decompensation, HCC and death).

Variables	Univariable analysis		Multivariable analysis^a
Variables	Hazard ratio (95% CI)	p-value	Hazard ratio (95% CI)	p-value
MEFIB-negative	Referent	–	Referent	–
MEFIB+ and MRI-PDFF ≥5%	11.9 (4.0–35.2)	<0.0001	20.0 (4.1–98.2)	0.0002
MEFIB+ and MRI-PDFF <5%	28.8 (8.9–93.5)	<0.0001	42.2 (7.5–235.5)	<0.0001

Abbreviations: CI, confidence interval; HCC, hepatocellular carcinoma; MEFIB, MRI combined with FIB-4; MRI-PDFF, magnetic resonance imaging-derived proton density fat fraction.

Adjusted for age, sex, BMI and race/ethnicity.