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. 2024 Jan 24;7:0295. doi: 10.34133/research.0295

Fig. 7.

Fig. 7.

Antitumor effect of G4DP in patient-derived xenografts model. (A) Diagram of the establishment of primary SCC cells. (B) Immunofluorescence staining of SERPINB3 (green) and the uptake and activation of G4DP in primary SCC cells. Scale bar = 20 μm. (C) Tumor-growth curves of different groups. (D) Photos of tumors harvested from mice in each group on day 14. (E) Tumor weight after various treatments. (F) The images of H&E staining for tumors after different treatments. Scale bar = 500 and 100 μm (inset), respectively. (G) Immunofluorescence staining of TUNEL (red) in tumor tissue and (H) the mean fluorescence intensity results. Scale bar = 100 μm. (I) Immunohistochemical staining of Ki67 in tumor tissue and (J) the relative quantified results. Scale bar = 100 and 50 μm (inset), respectively. *P < 0.05, **P < 0.01, ***P < 0.001, and ****P < 0.0001.