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. 2024 Jan 10;625(7996):768–777. doi: 10.1038/s41586-023-06899-4

Fig. 1. Three-dimensional morphological features of the nasopharyngeal and posterior nasal lymphatic plexuses.

Fig. 1

a, Immunofluorescence images of three views of whole mounts and a coronal section of the NPLP and posterior nasal lymphatic plexus of Prox1-GFP mice after staining for VEGFR3 and LYVE1. The flattened and condensed posterior nasal lymphatic plexus is in front of the NPLP distinguished by strong PROX1+, irregular and linearly shaped lymphatic valves (white arrowheads). The green arrowheads in the cross-section mark the borders of the NPLP. Scale bars, 500 μm. Similar findings were obtained from n = 6 mice in three independent experiments. b, Diagram of the inverted saddle shape of the NPLP. Anatomical positions are indicated at the bottom right. Ant., anterior; post., posterior; sup., superior; inf., inferior anatomical position.