Extended Data Fig. 1. Posterior margin of the palatal bone separates the nasopharyngeal lymphatic plexus from the posterior nasal lymphatic plexus.

a, Bright-field and fluorescence images of upper jaw and nasopharynx viewed from below (left) and laterally (upper right) and in a sagittal section through the palatal bone (lower right) of Prox1-GFP mice. The palatal bone is outlined (yellow dashed lines), and the posterior margin is marked with a red dashed line. The nasopharynx is outlined by a black dashed line. Anatomical positions are indicated in the upper left or right corner. Scale bars, 1 mm. Similar findings were obtained from n = 4 mice in two independent experiments. Ant., anterior; Post., posterior; Sup., superior; Inf., inferior anatomical position. b, Fluorescence images of coronal sections of the nasopharynx at the level of the posterior nasal lymphatic plexus (left, white arrowhead) and the level of the nasopharyngeal lymphatic plexus (right, green arrowhead) in Prox1-GFP mice. White dashed line box regions are enlarged in the lower panels. Scale bars, 200 μm. Similar findings were obtained from n = 4 mice in two independent experiments.