Table 1.
Maternal study demographics (n = 221)
| Variable | Overall |
|---|---|
| Maternal age (mean (s.d.)) | 32.68 (5.94) |
| Birth Outcome (%), n = 227a | |
| Live birth | 199 (87.7) |
| Miscarriage, Abortion, or Demise | 7 (3.1) |
| Loss to follow up (e.g., not delivered at UCLA) | 21 (9.3) |
| Maternal Ethnicity (%) | |
| Asian, mixed race, or other | 52 (24.0) |
| Black, Hispanic, or Latina | 110 (50.7) |
| White | 55 (25.3) |
| Maternal COVID severityb (%) | |
| Asymptomatic, Mild, Moderate | 192 (86.9) |
| Severe or Critical | 29 (13.1) |
| Maternal vaccination prior to delivery (%)c | 76 (37.3) |
| Maternal vaccination prior to infection (%)c | 70 (33.8) |
| Neonatal Respiratory Distress (%), n = 227a | 34 (17.0) |
aTwo hundred and twenty-one mothers were enrolled in our study, corresponding to 227 SARS-CoV-2 exposed fetuses due to multiple gestations.
bCOVID severity index was determined based on the NIH classification system14, as done by Thompson et al.4. Briefly, critical illness describes patients with respiratory failure or signs of multiple organ failure, severe illness was defined as patients with desaturations requiring supplemental oxygen, moderate illness included patients with dyspnea or who were admitted to an inpatient unit for COVID, mild illness describes symptomatic patients not meeting criteria for more severe disease, and asymptomatic individuals showed no symptoms.
cIndividuals were eligible to be included in both categories depending on the sequence of infection, vaccination, and delivery.