Table 1.
Overview of included studies and patient data
| Source | No. of included cases |
|---|---|
| Pajtler et al., Cancer Cell (2015) | 151 |
| Cavalli et al., Acta Neuropathol (2018) | 159 |
| Fukuoka et al., Acta Neuropathol Commun (2018) | 77 |
| Pajtler et al., Acta Neuropathol (2018) | 500 |
| Capper et al., Nature (2018) | 386 |
| Ghasemi et al., Acta Neuropathol (2019) | 6 |
| Raffeld et al., Acta Neuropathol Commun (2020) | 7 |
| Thomas et al., Acta Neuropathol (2021) | 31 |
| Ritzmann et al., Neuro Oncol (2022) | 35 |
| Pratt et al., Acta Neuropathol (2022) | 7 |
| Bockmayr et al., Neuro Oncol (2022) | 127 |
| Träger et al., Neuro Oncol (2023) | 118 |
| Sturm et al., Nat Med (2023) | 79 |
| HIT MED | 248 |
| Others | 92 |
| Total | 2023 |
| Age [years] | |
| Range, Median | 0–81, 8 |
| < 4 | 608 |
| 4–18 | 539 |
| > 18 | 602 |
| Not available | 274 |
| Sex | |
| Female | 761 |
| Male | 1053 |
| Not available | 209 |
| Ratio (male: female) | 1.38: 1 |
| Localization | |
| Supratentorial | 246 |
| Posterior fossa | 1357 |
| Spinal | 326 |
| Not available | 94 |
| WHO grade | |
| 1 | 82 |
| 2 | 489 |
| 3 | 592 |
| 4 | 1 |
| Not available | 859 |
| Molecular type | |
| EPN-ZFTA | 228 |
| ZFTA-RELA-A | 199 |
| ZFTA-RELA-B | 3 |
| ZFTA-FUS-C | 17 |
| ZFTA-FUS-D | 5 |
| ZFTA-FUS-E | 4 |
| EPN-YAP | 17 |
| ST-SE | 26 |
| EPN-PFA | 969 |
| PFA-1a | 146 |
| PFA-1b | 126 |
| PFA-1c | 138 |
| PFA-1d | 83 |
| PFA-1e | 118 |
| PFA-1f | 59 |
| PFA-2a | 147 |
| PFA-2b | 127 |
| PFA-2c | 25 |
| EPN-PFB | 308 |
| PFB-1 | 121 |
| PFB-2 | 53 |
| PFB-3 | 70 |
| PFB-4 | 47 |
| PFB-5 | 17 |
| PF-SE | 119 |
| SP-EPN | 143 |
| EPN-MYCN | 17 |
| MPE | 181 |
| MPE-A | 63 |
| MPE-B | 108 |
| SP-SE | 15 |
| SP-SE-A | 12 |
| SP-SE-B | 3 |