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Immunogenicity of PspA–IL-2 conjugates in C3H/HeJ micea
| Immunogen | IgG1 anti-PspA antibody titer
|
|
|---|---|---|
| C3H/HeJ | C3H/HeN | |
| PspA | 1,209 | 867 |
| PspA–IL-2 | 30,932 | 74,870 |
| PspA–GM-CSF | 103,790 | 34,226 |
Groups of five mice were immunized with 10 μg of PspA, PspA–IL-2, or PspA–GM-CSF and boosted 14 days later. Titers reflect averages of individual serum titrations obtained 14 days after the boost.
