Table 5.

Serum cytokines concentrations.

	Healthy donors (n = 500)	Achalasia (all) (n = 189)	Type I (n = 59)	Type II (n = 123)	Type III (n = 7)
Serum interleukins
IL-1$\beta$ , mean ± SD	13 ± 3	37 ± 13	32 ± 17	38 ± 18	42 ± 20
Median	1	1	1	1	17.3
Range	1.00–64.1	1.00–1002	1.00–324	1.00–1002	1.00–131
IL-6, mean ± SD	30 ± 5	49 ± 10	21 ± 5	40 ± 9	148 ± 45
Median	13.8	22.6	16.6	21.4	115
Range	1.42–156	1.42–354	1.95–76.0	1.42–354	35.0–324
IL-10, mean ± SD	9 ± 2	23 ± 3	30 ± 11	23 ± 3	9.8 ± 0.5
Median	7.1	11.4	15.9	11.6	9.5
Range	0.90–28.0	0.32–105	2.39–105	0.32–74.2	8.00–11.6
IL-17A mean ± SD	32 ± 8	120 ± 40	59 ± 16	109 ± 60	220 ± 51
Median	24	30.7	51	17.4	300
Range	0.23–137	2.86–979	20.9–106	2.86–979	57.3–303
IL-25 mean ± SD	7 ± 4	25 ± 9	26 ± 16	13 ± 4	13 ± 83
Median	1	1	1	1	1
Range	1.00–105	1.00–506	1.00–248	1.00–166	1.00–506
TNF-$\alpha$ mean ± SD	2.3 ± 0.3	3.7 ± 0.4	4.5 ± 1.1	3.2 ± 0.4	6.3 ± 1.4
Median	2.15	2.4	2.73	1.87	6
Range	2.10–7.46	0.2–19.8	0.8–19.8	0.2–14.1	1.4–11.8