Table 1.

Key frailty scores

	IMWG5	Revised Myeloma Comorbidity Index22	UK Myeloma Research Alliance Myeloma Risk Profile31	Mayo risk score24	IFM simplified frailty25
No. of patients	869	NR	2372	351	1618
Frail patients, %	30	NR	35	21	49
OS in frail patients	57% at 3 y	NR	mOS 20-25 mo	mOS 28 mo	mOS 42 mo
No. of groups	3	3	3	4	2
Parameters	Age, CCI, activities of daily living, independent activities of daily living	Estimated glomerular filtration rate, pulmonary function tests, frailty, age, cytogenetics, PS	Age, Revised International Staging System, C-reactive protein, PS	Age, N-terminal probrain natriuretic peptide, ECOG	Age, CCI, ECOG
Population	CT	CT, RW	CT	RW	CT

CT, clinical trial; mOS, median overall survival; NR, not reported; RW, real world.