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. 2024 Jan 25;40(1):4. doi: 10.1007/s10565-024-09841-0

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — As impairs lysosomal degradative function in mouse primary BMDC cultures. A Immunofluorescence images stained with Lyso-Tracker Red or Lyso-Sensor Green treated with 1 μM As for the times indicated. B, C Quantification of Lyso-Tracker and Lyso-Sensor fluorescence intensity. Summary data from at least five visual fields in each independent experiment. D RT-PCR analysis showing mRNA expression of lysosome membrane proton pump genes exposed to 1 μM As for the times indicated. All summary data are normalized to control, and values reflect Mean ± SEM, scale bar: 20 μm, ^*P < 0.05 compared with control (Ctr) group, n = 4