Table 1.

Effect of PHAR on liver parameters analyzed in serum of STAM mice. Serum albumin (Alb), alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (AP), and total protein levels (TP) were analyzed for the different experimental groups using a Beckman Coulter AU480. Data are mean ± S.D. (n = 6–7). ***p < 0.001 vs. CTRL; ###p < 0.001 vs. STAM-VEH according to two-way ANOVA followed by Bonferroni post-hoc test. Animals in this experiment were 8-week-old at the beginning of a 2-weeks treatment.

Groups	Alb (g/L)	ALT (U/L)	AST (U/L)	AP (U/L)	TP (g/L)
CTRL	22 ± 7.6	37.4 ± 10.3	86.7 ± 14.1	64.4 ± 13.9	35.6 ± 14.9
CTRL-PHAR	25 ± 1.2	46.5 ± 18.3	79.4 ± 14.8	59.5 ± 15.2	46.6 ± 3.3
STAM-VEH	18.5 ± 1.0	324.7 ± 70.8***	101.0 ± 20.8	125.2 ± 72.3	35.2 ± 6.7
STAM-PHAR	21.5 ± 2.6	185.3 ± 64.1###	95.3 ± 7.8	103.5 ± 11.5	49.2 ± 10.4