TABLE 2.
Hazard rate ratios for associations between lifestyle‐associated variables and meningioma.
| Comparison | Univariate analyses | Multivariable analyses | ||
|---|---|---|---|---|
| RR (95% CI) | P for comparison | RR (95% CI) | P for comparison | |
| Body mass index | ||||
| Overweight (25–29.9) vs. normal | 1.8 (1.0–3.3) | 0.06 | 1.3 (0.7–2.4) | 0.42 |
| Obesity (≥30) vs. normal | 2.5 (1.5–4.4) | 0.001 | 1.2 (0.7–2.1) | 0.59 |
| Body fat percentage | ||||
| Pre‐obesity vs. normal | 2.4 (0.8–6.9) | 0.11 | 1.1 (0.4–3.3) | 0.81 |
| Obesity vs. normal | 6.3 (2.5–15.6) | <0.001 | 1.8 (0.7–4.7) | 0.23 |
| Self‐reported physical activity | ||||
| 3–6 vs. 0–3 METh/week | 0.7 (0.4–1.3) | 0.26 | NA | NA |
| ≥6 vs. 0–3 METh/week | 0.7 (0.5–1.2) | 0.20 | NA | NA |
| 6‐min walk test | ||||
| Quartile 2 vs. 1 | 0.6 (0.4–1.1) | 0.09 | 0.8 (0.5–1.5) | 0.53 |
| Quartile 3 vs. 1 | 0.5 (0.3–0.9) | 0.02 | 0.8 (0.4–1.4) | 0.43 |
| Quartile 4 vs. 1 | 0.4 (0.2–0.7) | 0.002 | 0.7 (0.4–1.4) | 0.33 |
| Grip strength | ||||
| Moderate vs. low | 0.4 (0.2–0.7) | 0.002 | 0.6 (0.3–1.1) | 0.12 |
| High vs. low | 0.5 (0.3–0.7) | 0.001 | 0.8 (0.3–1.7) | 0.49 |
| Knee extension | ||||
| Moderate vs. low | 0.5 (0.3–0.9) | 0.03 | 0.7 (0.4–1.1) | 0.14 |
| High vs. low | 0.3 (0.2–0.5) | <0.001 | 0.5 (0.2–1.0) | 0.04 |
| Never smoker | 1.8 (1.1–3.1) | 0.02 | 1.6 (0.9–2.9) | 0.11 |
| Absence of risky drinking | 2.3 (1.4–3.9) | 0.002 | 1.3 (0.7–2.3) | 0.36 |
Note: One lifestyle variable was included in each model. All models were adjusted for sex, age at diagnosis and baseline assessment, treatment decade, and childhood cancer treatment exposures.
Abbreviations: BMI, body mass index; CNS, central nervous system; MET, metabolic equivalent task; RR, relative risk.