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. Author manuscript; available in PMC: 2024 Jan 25.
Published in final edited form as: Cell Rep. 2023 Dec 4;42(12):113535. doi: 10.1016/j.celrep.2023.113535

Figure 7. Loss of MST1/2 alters fasting glycogen metabolism.

Figure 7.

(A) Immunoblot for the indicated proteins using lysates from livers taken from Stk3f/f;Stk4f/f, Alb-Cre−/− (Flox) and Stk3f/f;Stk4f/f, Alb-Cre+/− (DKO) that were fasted for 18 h (Fast) and then euthanized or provided food for 4 h (Fed). N = 4.

(B) Quantification of the ratio of phosphorylated glycogen synthase (pGS) to total GS using band intensity for the Fasted mice in (A). The ratio was normalized to the average of the Fasted Flox mice. (C–E) Hepatic GS activity (C; N = 4), glycogen phosphorylase (GP) activity (D; N = 4), and glycogen content (E; N = 10) were measured from Fasted Flox and DKO mice.

Data are presented as mean ± SEMs. Comparisons made via Student’s t test.