Comparison of ADCs with X–Asn/Gln linkers.
| ADC | Dipeptide | HIC Ret time/min | Agg/% |
|---|---|---|---|
| ADC35 | Ala–Asn | 6.45 | 6.3 |
| ADC30 | Ala–Gln | 6.38 | 3.1 |
| ADC45 | Ser–Asn | 6.19 | 12.7 |
| ADC46 | Ser–Gln | 6.29 | 8.8 |
| ADC52 | Val–Asn | 6.46 | 14.2 |
| ADC53 | Val–Gln | 6.66 | 5.8 |
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