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. 2024 Jan 6;9(3):3642–3668. doi: 10.1021/acsomega.3c07655

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© 2024 The Authors. Published by American Chemical Society

Permits non-commercial access and re-use, provided that author attribution and integrity are maintained; but does not permit creation of adaptations or other derivative works (https://creativecommons.org/licenses/by-nc-nd/4.0/).

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Effect of Fip.Cr against K⁺ (80 mM) and phenylephrine (1 μM) induced contractions on (A) endothelium-intact and (B) endothelium-denuded aortic tissue preparation. (C) Vasorelaxant effect of Fip.Cr with L-NAME (10 μM) pretreatment endothelium-intact rat aorta against phenylephrine (1 μM) induced contractions. (D) Effect of verapamil against K⁺ (80 mM) and phenylephrine (1 μM) induced contractions on endothelium-intact aortic tissue preparation. Values are presented as the mean ± SD (n = 5).